The embryonic stem cell controversy and beyond
Readers of the OUTLOOK are familiar with the heated public controversy over the use of human embryos to harvest stem cells for medical research. What are called embryos are actually ova fertilized in a Petri dish. The zygotes are forced to undergo cell division, frozen and stored on a shelf for possible use later, usually for fertility treatment-- but never implanted in a human uterus. For that reason they are not really embryos, technically speaking. The point of interest is that they are currently the best source of "pluripotent stem cells," meaning cells that have the capacity to become any type of cell in the body when properly treated. These cells are needed to develop effective treatments for diseases that already include Alzheimer's, Parkinson's, juvenile diabetes, muscular dystrophy, and paralysis resulting from spinal cord injury.
The sticking point for those who object, including President George W. Bush, is that they believe these fertilized eggs possess the value of human beings and the process of extracting stem cells from them kills human life. Many scientists, on the other hand, have a hard time imagining how a still undifferentiated zygote that will never be implanted in a uterus qualifies as a human being. An estimated 400,000 fertilized ova or embryos are stored in U.S. freezers today, and most of them will be discarded.
Stem cell research is rapidly advancing in many other countries, notably the United Kingdom and South Korea, and in private U.S. labs that do not receive federal funding. Ironically, one of the effects of the Bush administration's ban on embryonic stem cell research funding is that the research is now barreling on outside the ethical guidelines established early in the game by the National Institutes of Health and approved by the Clinton administration. Those guidelines made it clear that only embryos could be used that were created for the purpose of fertility treatment and were in excess of clinical need. When stem cell research is removed from NIH oversight into the private sector, such ethical restrictions are not obligatory.